2qrg

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Image:2qrg.png

Template:STRUCTURE 2qrg

Glycogen Phosphorylase b in complex with (1R)-3'-(4-methoxyphenyl)-spiro[1,5-anhydro-D-glucitol-1,5'-isoxazoline]

Template:ABSTRACT PUBMED 19781947

About this Structure

2QRG is a 1 chain structure of sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

  • Benltifa M, Hayes JM, Vidal S, Gueyrard D, Goekjian PG, Praly JP, Kizilis G, Tiraidis C, Alexacou KM, Chrysina ED, Zographos SE, Leonidas DD, Archontis G, Oikonomakos NG. Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors. Bioorg Med Chem. 2009 Oct 15;17(20):7368-80. Epub 2009 Sep 2. PMID:19781947 doi:10.1016/j.bmc.2009.08.060

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