1izh

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Template:STRUCTURE 1izh

Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants

Template:ABSTRACT PUBMED 12460574

About this Structure

1IZH is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Weber J, Mesters JR, Lepsik M, Prejdova J, Svec M, Sponarova J, Mlcochova P, Skalicka K, Strisovsky K, Uhlikova T, Soucek M, Machala L, Stankova M, Vondrasek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J. Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains. J Mol Biol. 2002 Dec 6;324(4):739-54. PMID:12460574

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