2ntr

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Image:2ntr.png

Template:STRUCTURE 2ntr

Crystal structure of Human Bace-1 bound to inhibitor

Template:ABSTRACT PUBMED 17112725

About this Structure

2NTR is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • McGaughey GB, Colussi D, Graham SL, Lai MT, Munshi SK, Nantermet PG, Pietrak B, Rajapakse HA, Selnick HG, Stauffer SR, Holloway MK. Beta-secretase (BACE-1) inhibitors: accounting for 10s loop flexibility using rigid active sites. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1117-21. Epub 2006 Nov 6. PMID:17112725 doi:10.1016/j.bmcl.2006.11.003

Page seeded by OCA on Tue Feb 17 05:49:47 2009

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