2tsr

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Template:STRUCTURE 2tsr

THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX

Template:ABSTRACT PUBMED 9894005

About this Structure

2TSR is a 4 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Sotelo-Mundo RR, Ciesla J, Dzik JM, Rode W, Maley F, Maley GF, Hardy LW, Montfort WR. Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug. Biochemistry. 1999 Jan 19;38(3):1087-94. PMID:9894005 doi:10.1021/bi981881d

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