3ezr

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Template:STRUCTURE 3ezr

Contents

CDK-2 with indazole inhibitor 17 bound at its active site

Template:ABSTRACT PUBMED 19097791

About this Structure

3ezr is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Trujillo JI, Kiefer JR, Huang W, Thorarensen A, Xing L, Caspers NL, Day JE, Mathis KJ, Kretzmer KK, Reitz BA, Weinberg RA, Stegeman RA, Wrightstone A, Christine L, Compton R, Li X. 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor. Bioorg Med Chem Lett. 2009 Feb 1;19(3):908-11. Epub 2008 Dec 6. PMID:19097791 doi:10.1016/j.bmcl.2008.11.105

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