2gfx

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Image:2gfx.png

Template:STRUCTURE 2gfx

Structure of E. coli FabF(C163Q) in complex with Platensimycin

Template:ABSTRACT PUBMED 16710421

About this Structure

2GFX is a 1 chain structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Wang J, Soisson SM, Young K, Shoop W, Kodali S, Galgoci A, Painter R, Parthasarathy G, Tang YS, Cummings R, Ha S, Dorso K, Motyl M, Jayasuriya H, Ondeyka J, Herath K, Zhang C, Hernandez L, Allocco J, Basilio A, Tormo JR, Genilloud O, Vicente F, Pelaez F, Colwell L, Lee SH, Michael B, Felcetto T, Gill C, Silver LL, Hermes JD, Bartizal K, Barrett J, Schmatz D, Becker JW, Cully D, Singh SB. Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature. 2006 May 18;441(7091):358-61. PMID:16710421 doi:10.1038/nature04784

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