2vqv

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Template:STRUCTURE 2vqv

Contents 1 STRUCTURE OF HDAC4 CATALYTIC DOMAIN WITH A GAIN-OF-FUNCTION MUTATION BOUND TO A HYDROXAMIC ACID INHIBITOR 2 About this Structure 3 See Also 4 Reference

STRUCTURE OF HDAC4 CATALYTIC DOMAIN WITH A GAIN-OF-FUNCTION MUTATION BOUND TO A HYDROXAMIC ACID INHIBITOR

Template:ABSTRACT PUBMED 18614528

About this Structure

2vqv is a 2 chain structure of Histone deacetylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Histone deacetylase

Reference

• Bottomley MJ, Lo Surdo P, Di Giovine P, Cirillo A, Scarpelli R, Ferrigno F, Jones P, Neddermann P, De Francesco R, Steinkuhler C, Gallinari P, Carfi A. Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc-binding domain. J Biol Chem. 2008 Sep 26;283(39):26694-704. Epub 2008 Jul 8. PMID:18614528 doi:http://dx.doi.org/10.1074/jbc.M803514200