3iw4
From Proteopedia
Crystal structure of PKC alpha in complex with NVP-AEB071
Template:ABSTRACT PUBMED 19827831
About this Structure
3IW4 is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wagner J, von Matt P, Sedrani R, Albert R, Cooke N, Ehrhardt C, Geiser M, Rummel G, Stark W, Strauss A, Cowan-Jacob SW, Beerli C, Weckbecker G, Evenou JP, Zenke G, Cottens S. Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5 -dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes. J Med Chem. 2009 Oct 22;52(20):6193-6. PMID:19827831 doi:10.1021/jm901108b
Page seeded by OCA on Thu Jan 28 14:38:38 2010
Categories: Homo sapiens | Protein kinase C | Cowan-Jacob, S W. | Rummel, G. | Stark, W. | Strauss, A. | Atp-binding | Calcium | Cell membrane | Cytoplasm | Kinase | Membrane | Metal-binding | Nucleotide-binding | Phorbol-ester binding | Phosphoprotein | Polymorphism | Serine/threonine-protein kinase | Transferase | Zinc | Zinc-finger