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2oiq

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Template:STRUCTURE 2oiq

Contents

Crystal Structure of chicken c-Src kinase domain in complex with the cancer drug imatinib.

Template:ABSTRACT PUBMED 17355866

About this Structure

2oiq is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.

See Also

Reference

  • Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J. c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty. Structure. 2007 Mar;15(3):299-311. PMID:17355866 doi:10.1016/j.str.2007.01.015

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