2i42

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Template:STRUCTURE 2i42

Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue

Template:ABSTRACT PUBMED 8637902

About this Structure

2i42 is a 1 chain structure with sequence from Yersinia enterocolitica. Full crystallographic information is available from OCA.

Reference

  • Denu JM, Lohse DL, Vijayalakshmi J, Saper MA, Dixon JE. Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis. Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2493-8. PMID:8637902
  • Schubert HL, Fauman EB, Stuckey JA, Dixon JE, Saper MA. A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase. Protein Sci. 1995 Sep;4(9):1904-13. PMID:8528087
  • Zhang ZY, Wang Y, Dixon JE. Dissecting the catalytic mechanism of protein-tyrosine phosphatases. Proc Natl Acad Sci U S A. 1994 Mar 1;91(5):1624-7. PMID:8127855

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