1pyn

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Image:1pyn.png

Template:STRUCTURE 1pyn

DUAL-SITE POTENT, SELECTIVE PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR USING A LINKED FRAGMENT STRATEGY AND A MALONATE HEAD ON THE FIRST SITE

Template:ABSTRACT PUBMED 12951078

About this Structure

1PYN is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pei Z, Li X, Liu G, Abad-Zapatero C, Lubben T, Zhang T, Ballaron SJ, Hutchins CW, Trevillyan JM, Jirousek MR. Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3129-32. PMID:12951078

Page seeded by OCA on Tue Feb 17 09:04:56 2009

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