3klh

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Image:3klh.png

Template:STRUCTURE 3klh

Crystal structure of AZT-Resistant HIV-1 Reverse Transcriptase crosslinked to post-translocation AZTMP-Terminated DNA (COMPLEX P)

Template:ABSTRACT PUBMED 20852643

About this Structure

3klh is a 6 chain structure with sequence from Human immunodeficiency virus 1 and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908

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