3mpt

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Template:STRUCTURE 3mpt

Crystal structure of P38 kinase in complex with a pyrrole-2-carboxamide inhibitor

Template:ABSTRACT PUBMED 20570148

About this Structure

3MPT is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Down K, Bamborough P, Alder C, Campbell A, Christopher JA, Gerelle M, Ludbrook S, Mallett D, Mellor G, Miller DD, Pearson R, Ray K, Solanke Y, Somers D. The discovery and initial optimisation of pyrrole-2-carboxamides as inhibitors of p38alpha MAP kinase. Bioorg Med Chem Lett. 2010 Jul 1;20(13):3936-40. Epub 2010 May 10. PMID:20570148 doi:10.1016/j.bmcl.2010.05.011

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