1x7a

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Template:STRUCTURE 1x7a

Porcine Factor IXa Complexed to 1-{3-[amino(imino)methyl]phenyl}-N-[4-(1H-benzimidazol-1-yl)-2-fluorophenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide

Template:ABSTRACT PUBMED 15454208

About this Structure

1X7A is a 2 chains structure of sequences from Sus scrofa. Full crystallographic information is available from OCA.

Reference

  • Smallheer JM, Alexander RS, Wang J, Wang S, Nakajima S, Rossi KA, Smallwood A, Barbera F, Burdick D, Luettgen JM, Knabb RM, Wexler RR, Jadhav PK. SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5263-7. PMID:15454208 doi:10.1016/j.bmcl.2004.08.034

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