1lzq

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Image:1lzq.png

Template:STRUCTURE 1lzq

Crystal structure of the complex of mutant HIV-1 protease (A71V, V82T, I84V) with an ethylenamine peptidomimetic inhibitor BOC-PHE-PSI[CH2CH2NH]-PHE-GLU-PHE-NH2

Template:ABSTRACT PUBMED 12699382

About this Structure

1LZQ is a 3 chains structure of sequences from Human immunodeficiency virus. Full crystallographic information is available from OCA.

Reference

  • Skalova T, Hasek J, Dohnalek J, Petrokova H, Buchtelova E, Duskova J, Soucek M, Majer P, Uhlikova T, Konvalinka J. An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study. J Med Chem. 2003 Apr 24;46(9):1636-44. PMID:12699382 doi:10.1021/jm021079g

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