1n9a

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Image:1n9a.png

Template:STRUCTURE 1n9a

Farnesyltransferase complex with tetrahydropyridine inhibitors

Template:ABSTRACT PUBMED 12657283

About this Structure

1N9A is a 2 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Gwaltney SL 2nd, O'Connor SJ, Nelson LT, Sullivan GM, Imade H, Wang W, Hasvold L, Li Q, Cohen J, Gu WZ, Tahir SK, Bauch J, Marsh K, Ng SC, Frost DJ, Zhang H, Muchmore S, Jakob CG, Stoll V, Hutchins C, Rosenberg SH, Sham HL. Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1363-6. PMID:12657283

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