1ec0

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Image:1ec0.png

Template:STRUCTURE 1ec0

HIV-1 protease in complex with the inhibitor bea403

Template:ABSTRACT PUBMED 15560801

About this Structure

1EC0 is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Lindberg J, Pyring D, Lowgren S, Rosenquist A, Zuccarello G, Kvarnstrom I, Zhang H, Vrang L, Classon B, Hallberg A, Samuelsson B, Unge T. Symmetric fluoro-substituted diol-based HIV protease inhibitors. Ortho-fluorinated and meta-fluorinated P1/P1'-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacy. Eur J Biochem. 2004 Nov;271(22):4594-602. PMID:15560801 doi:10.1111/j.1432-1033.2004.04431.x

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