2agt

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Image:2agt.png

Template:STRUCTURE 2agt

Aldose Reductase Mutant Leu 300 Pro complexed with Fidarestat

Template:ABSTRACT PUBMED 16134934

About this Structure

2AGT is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Petrova T, Steuber H, Hazemann I, Cousido-Siah A, Mitschler A, Chung R, Oka M, Klebe G, El-Kabbani O, Joachimiak A, Podjarny A. Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex. J Med Chem. 2005 Sep 8;48(18):5659-65. PMID:16134934 doi:10.1021/jm050424+

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