2hl3

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Image:2hl3.png

Template:STRUCTURE 2hl3

Contents

Crystal structure of the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued) in complex with human EB1 C-terminal hexapeptide

Template:ABSTRACT PUBMED 16949363

Disease

Known disease associated with this structure: Neuropathy, distal hereditary motor, type VIIB OMIM:[601143], Amyotrophic lateral sclerosis, susceptibility to OMIM:[601143]

About this Structure

2HL3 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Honnappa S, Okhrimenko O, Jaussi R, Jawhari H, Jelesarov I, Winkler FK, Steinmetz MO. Key interaction modes of dynamic +TIP networks. Mol Cell. 2006 Sep 1;23(5):663-71. PMID:16949363 doi:10.1016/j.molcel.2006.07.013

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