3hk6
From Proteopedia
Crystal structure of murine thrombin mutant W215A/E217A (two molecules in the asymmetric unit)
Template:ABSTRACT PUBMED 19586901
About this Structure
3hk6 is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Gandhi PS, Page MJ, Chen Z, Bush-Pelc L, Di Cera E. Mechanism of the anticoagulant activity of thrombin mutant W215A/E217A. J Biol Chem. 2009 Sep 4;284(36):24098-105. Epub 2009 Jul 8. PMID:19586901 doi:10.1074/jbc.M109.025403
- Pineda AO, Chen ZW, Caccia S, Cantwell AM, Savvides SN, Waksman G, Mathews FS, Di Cera E. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem. 2004 Sep 17;279(38):39824-8. Epub 2004 Jul 13. PMID:15252033 doi:http://dx.doi.org/10.1074/jbc.M407272200
Categories: Mus musculus | Thrombin | Bush-Pelc, L. | Cera, E Di. | Chen, Z. | Gandhi, P S. | Page, M J. | Acute phase | Blood coagulation | Calcium | Cleavage on pair of basic residue | Disulfide bond | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Kringle | Protease | Serine protease | Zymogen
