2kbi

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Template:STRUCTURE 2kbi

Contents 1 Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5 2 Disease 3 About this Structure 4 Reference

Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5

Template:ABSTRACT PUBMED 19074138

Disease

Known disease associated with this structure: Brugada syndrome 1 OMIM:[600163], Cardiomyopathy, dilated, 1E OMIM:[600163], Heart block, nonprogressive OMIM:[600163], Heart block, progressive, type IA OMIM:[600163], Long QT syndrome-3 OMIM:[600163], Sick sinus syndrome 1 OMIM:[600163], Ventricular fibrillation, idiopathic OMIM:[600163], Sudden infant death syndrome, susceptibility to OMIM:[600163]

About this Structure

2KBI is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Chagot B, Potet F, Balser JR, Chazin WJ. Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5. J Biol Chem. 2009 Mar 6;284(10):6436-45. Epub 2008 Dec 11. PMID:19074138 doi:10.1074/jbc.M807747200

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