2h4k

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Template:STRUCTURE 2h4k

Crystal structure of PTP1B with a monocyclic thiophene inhibitor

Template:ABSTRACT PUBMED 16806920

About this Structure

2H4K is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wan ZK, Lee J, Xu W, Erbe DV, Joseph-McCarthy D, Follows BC, Zhang YL. Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: capturing interactions with Asp48. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4941-5. Epub 2006 Jun 27. PMID:16806920 doi:http://dx.doi.org/10.1016/j.bmcl.2006.06.051

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