3b9f
From Proteopedia
Contents |
1.6 A structure of the PCI-thrombin-heparin complex
Template:ABSTRACT PUBMED 18362344
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
3B9F is a 3 chains structure of sequences from Bos taurus and Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Li W, Adams TE, Nangalia J, Esmon CT, Huntington JA. Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4661-6. Epub 2008 Mar 24. PMID:18362344
Page seeded by OCA on Tue Feb 17 15:51:49 2009
Categories: Bos taurus | Homo sapiens | Thrombin | Adams, T E. | Huntington, J A. | Li, W. | Acute phase | Blood coagulation | Calcium | Cleavage on pair of basic residue | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydrolase/hydrolase inhibitor complex | Kringle | Michaelis complex | Polymorphism | Protease | Secreted | Serine protease | Zymogen