This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3hs4
From Proteopedia
Human carbonic anhydrase II complexed with acetazolamide
Template:ABSTRACT PUBMED 19851004
About this Structure
3hs4 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sippel KH, Robbins AH, Domsic J, Genis C, Agbandje-McKenna M, McKenna R. High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1;65(Pt, 10):992-5. Epub 2009 Sep 25. PMID:19851004 doi:10.1107/S1744309109036665
- Vidgren J, Liljas A, Walker NP. Refined structure of the acetazolamide complex of human carbonic anhydrase II at 1.9 A. Int J Biol Macromol. 1990 Dec;12(6):342-4. PMID:2128470
Categories: Carbonate dehydratase | Homo sapiens | Agbandje-McKenna, M. | Domsic, J. | Genis, C. | McKenna, R. | Robbins, A H. | Sippel, K H. | 4-thiadiazole-2-sulfonamide | 5-acetamido-1 | Acetazolamide | Acetylation | Ca 2 | Ca ii | Carbonic anhydrase 2 | Carbonic anhydrase ii | Cytoplasm | Disease mutation | Lyase | Metal-binding | Polymorphism | Zinc
