2gab

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Image:2gab.png

Template:STRUCTURE 2gab

Human Transthyretin (TTR) Complexed with Hydroxylated polychlorinated Biphenyl-4-hydroxy-3,3',5,4'-tetrachlorobiphenyl

Template:ABSTRACT PUBMED 15610856

About this Structure

2GAB is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Purkey HE, Palaninathan SK, Kent KC, Smith C, Safe SH, Sacchettini JC, Kelly JW. Hydroxylated polychlorinated biphenyls selectively bind transthyretin in blood and inhibit amyloidogenesis: rationalizing rodent PCB toxicity. Chem Biol. 2004 Dec;11(12):1719-28. PMID:15610856 doi:http://dx.doi.org/10.1016/j.chembiol.2004.10.009

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