3ioi

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Image:3ioi.png

Template:STRUCTURE 3ioi

Contents

Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (1GW)

Template:ABSTRACT PUBMED 20364127

Disease

Known disease associated with this structure: Blood group, ABO system OMIM:[110300]

About this Structure

3IOI is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pesnot T, Jorgensen R, Palcic MM, Wagner GK. Structural and mechanistic basis for a new mode of glycosyltransferase inhibition. Nat Chem Biol. 2010 May;6(5):321-3. Epub 2010 Apr 4. PMID:20364127 doi:10.1038/nchembio.343

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