2zdz
From Proteopedia
X-ray structure of Bace-1 in complex with compound 3.b.10
Template:ABSTRACT PUBMED 18162398
About this Structure
2ZDZ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets., Cole DC, Stock JR, Chopra R, Cowling R, Ellingboe JW, Fan KY, Harrison BL, Hu Y, Jacobsen S, Jennings LD, Jin G, Lohse PA, Malamas MS, Manas ES, Moore WJ, O'Donnell MM, Olland AM, Robichaud AJ, Svenson K, Wu J, Wagner E, Bard J, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1063-6. Epub 2007 Dec 10. PMID:18162398
Page seeded by OCA on Wed Dec 10 14:57:26 2008
