3bjc

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Image:3bjc.png

Template:STRUCTURE 3bjc

Crystal structure of the PDE5A catalytic domain in complex with a novel inhibitor

Template:ABSTRACT PUBMED 18346713

About this Structure

3BJC is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chen G, Wang H, Robinson H, Cai J, Wan Y, Ke H. An insight into the pharmacophores of phosphodiesterase-5 inhibitors from synthetic and crystal structural studies. Biochem Pharmacol. 2008 May 1;75(9):1717-28. Epub 2008 Feb 12. PMID:18346713 doi:10.1016/j.bcp.2008.01.019

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