2g28

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Image:2g28.png

Template:STRUCTURE 2g28

E. Coli Pyruvate Dehydrogenase H407A variant Phosphonolactylthiamin Diphosphate Complex

Template:ABSTRACT PUBMED 16531404

About this Structure

2G28 is a 2 chains structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Arjunan P, Sax M, Brunskill A, Chandrasekhar K, Nemeria N, Zhang S, Jordan F, Furey W. A thiamin-bound, pre-decarboxylation reaction intermediate analogue in the pyruvate dehydrogenase E1 subunit induces large scale disorder-to-order transformations in the enzyme and reveals novel structural features in the covalently bound adduct. J Biol Chem. 2006 Jun 2;281(22):15296-303. Epub 2006 Mar 10. PMID:16531404 doi:http://dx.doi.org/10.1074/jbc.M600656200

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