3i7e

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Image:3i7e.png

Template:STRUCTURE 3i7e

Co-crystal structure of HIV-1 protease bound to a mutant resistant inhibitor UIC-98038

Template:ABSTRACT PUBMED 19746963

About this Structure

3I7E is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Ghosh AK, Kulkarni S, Anderson DD, Hong L, Baldridge A, Wang YF, Chumanevich AA, Kovalevsky AY, Tojo Y, Masayuki A, Koh Y, Tang J, Weber IT, Mitsuya H. Design, Synthesis, Protein-Ligand X-ray Structure, and Biological Evaluation of a Series of Novel Macrocyclic Human Immunodeficiency Virus-1 Protease Inhibitors to Combat Drug Resistance. J Med Chem. 2009 Sep 11. PMID:19746963 doi:10.1021/jm900695w

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