3dtw

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Template:STRUCTURE 3dtw

Contents 1 Crystal structure of the VEGFR2 kinase domain in complex with a benzisoxazole inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure of the VEGFR2 kinase domain in complex with a benzisoxazole inhibitor

Template:ABSTRACT PUBMED 18723346

About this Structure

3dtw is a 2 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Vascular Endothelial Growth Factor Receptor

Reference

• Kunz RK, Rumfelt S, Chen N, Zhang D, Tasker AS, Burli R, Hungate R, Yu V, Nguyen Y, Whittington DA, Meagher KL, Plant M, Tudor Y, Schrag M, Xu Y, Ng GY, Hu E. Discovery of amido-benzisoxazoles as potent c-Kit inhibitors. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5115-7. Epub 2008 Jul 31. PMID:18723346 doi:10.1016/j.bmcl.2008.07.111