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3exo
From Proteopedia
Contents |
Crystal structure of BACE1 bound to inhibitor
Template:ABSTRACT PUBMED 19036583
About this Structure
3exo is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Steele TG, Hills ID, Nomland AA, de Leon P, Allison T, McGaughey G, Colussi D, Tugusheva K, Haugabook SJ, Espeseth AS, Zuck P, Graham SL, Stachel SJ. Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement. Bioorg Med Chem Lett. 2009 Jan 1;19(1):17-20. Epub 2008 Nov 13. PMID:19036583 doi:10.1016/j.bmcl.2008.11.027
Categories: Homo sapiens | Memapsin 2 | Allison, T J. | Aspartyl protease | Bace 1 | Beta secretase | Glycoprotein | Hydrolase | Membrane | Protease | Transmembrane | Zymogen
