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3vhe

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Image:3vhe.jpg

Template:STRUCTURE 3vhe

Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.

Template:ABSTRACT PUBMED 20833055

About this Structure

3vhe is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Oguro Y, Miyamoto N, Okada K, Takagi T, Iwata H, Awazu Y, Miki H, Hori A, Kamiyama K, Imamura S. Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation. Bioorg Med Chem. 2010 Oct 15;18(20):7260-73. Epub 2010 Aug 13. PMID:20833055 doi:10.1016/j.bmc.2010.08.017

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OCA

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