2pdh

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Image:2pdh.png

Template:STRUCTURE 2pdh

Human aldose reductase mutant L300P complexed with uracil-type inhibitor at 1.45 A.

Template:ABSTRACT PUBMED 18495158

About this Structure

2PDH is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Steuber H, Heine A, Podjarny A, Klebe G. Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features. J Mol Biol. 2008 Jun 20;379(5):991-1016. Epub 2008 Apr 8. PMID:18495158 doi:10.1016/j.jmb.2008.03.063

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