1zx1

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Image:1zx1.png

Template:STRUCTURE 1zx1

Contents

Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954

Template:ABSTRACT PUBMED 016192279

About this Structure

1zx1 is a 2 chain structure of Quinone reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Fieulaine S, Juillan-Binard C, Serero A, Dardel F, Giglione C, Meinnel T, Ferrer JL. The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms. J Biol Chem. 2005 Dec 23;280(51):42315-24. Epub 2005 Sep 28. PMID:16192279 doi:10.1074/jbc.M507155200
  • Middleton MR, Knox R, Cattell E, Oppermann U, Midgley R, Ali R, Auton T, Agarwal R, Anderson D, Sarker D, Judson I, Osawa T, Spanswick VJ, Davies S, Hartley JA, Kerr DJ. Quinone oxidoreductase-2-mediated prodrug cancer therapy. Sci Transl Med. 2010 Jul 14;2(40):40ra50. PMID:20630857 doi:10.1126/scitranslmed.3000615

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