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2zec

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Image:2zec.png

Template:STRUCTURE 2zec

Contents

Potent, Nonpeptide Inhibitors of Human Mast Cell Tryptase

Template:ABSTRACT PUBMED 18272363

About this Structure

2zec is a 4 chain structure of Tryptase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Costanzo MJ, Yabut SC, Zhang HC, White KB, de Garavilla L, Wang Y, Minor LK, Tounge BA, Barnakov AN, Lewandowski F, Milligan C, Spurlino JC, Abraham WM, Boswell-Smith V, Page CP, Maryanoff BE. Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2114-21. Epub 2008 Jan 30. PMID:18272363 doi:10.1016/j.bmcl.2008.01.093

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OCA

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