1xx9

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Image:1xx9.png

Template:STRUCTURE 1xx9

Contents

Crystal Structure of the FXIa Catalytic Domain in Complex with EcotinM84R

Template:ABSTRACT PUBMED 15545266

Disease

Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]

About this Structure

1XX9 is a 4 chains structure of sequences from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jin L, Pandey P, Babine RE, Gorga JC, Seidl KJ, Gelfand E, Weaver DT, Abdel-Meguid SS, Strickler JE. Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions. J Biol Chem. 2005 Feb 11;280(6):4704-12. Epub 2004 Nov 15. PMID:15545266 doi:10.1074/jbc.M411309200

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