3igv
From Proteopedia
Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor
Template:ABSTRACT PUBMED 19796938
About this Structure
3IGV is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.
Reference
- Ellis DA, Blazel JK, Tran CV, Ruebsam F, Murphy DE, Li LS, Zhao J, Zhou Y, McGuire HM, Xiang AX, Webber SE, Zhao Q, Han Q, Kissinger CR, Lardy M, Gobbi A, Showalter RE, Shah AM, Tsan M, Patel RA, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6047-52. Epub 2009 Sep 17. PMID:19796938 doi:10.1016/j.bmcl.2009.09.051
Page seeded by OCA on Wed Dec 9 15:00:07 2009
Categories: RNA-directed RNA polymerase | Viruses | Han, Q. | Kissinger, C R. | Showalter, R E. | Zhao, Q. | Antiviral | Atp-binding | Disulfide bond | Host-virus interaction | Hydrolase | Metal binding | Metal-binding | Multifunctional enzyme | Nucleotide-binding | Nucleotidyltransferase | Nucleus | Protein-ligand complex | Rna replication | Rna-binding | Rna-directed rna polymerase | Transcription | Transcription regulation | Transferase | Viral nucleoprotein | Virion | Zinc
