3igv
From Proteopedia
Contents |
Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor
Template:ABSTRACT PUBMED 19796938
About this Structure
3igv is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.
See Also
Reference
- Ellis DA, Blazel JK, Tran CV, Ruebsam F, Murphy DE, Li LS, Zhao J, Zhou Y, McGuire HM, Xiang AX, Webber SE, Zhao Q, Han Q, Kissinger CR, Lardy M, Gobbi A, Showalter RE, Shah AM, Tsan M, Patel RA, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6047-52. Epub 2009 Sep 17. PMID:19796938 doi:10.1016/j.bmcl.2009.09.051
Categories: RNA-directed RNA polymerase | Viruses | Han, Q. | Kissinger, C R. | Showalter, R E. | Zhao, Q. | Antiviral | Atp-binding | Disulfide bond | Host-virus interaction | Hydrolase | Metal binding | Metal-binding | Multifunctional enzyme | Nucleotide-binding | Nucleotidyltransferase | Nucleus | Protein-ligand complex | Rna replication | Rna-binding | Rna-directed rna polymerase | Transcription | Transcription regulation | Transferase | Viral nucleoprotein | Virion
