3ika

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Image:3ika.jpg

Template:STRUCTURE 3ika

Crystal Structure of EGFR 696-1022 T790M Mutant Covalently Binding to WZ4002

Template:ABSTRACT PUBMED 20033049

About this Structure

3IKA is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhou W, Ercan D, Chen L, Yun CH, Li D, Capelletti M, Cortot AB, Chirieac L, Iacob RE, Padera R, Engen JR, Wong KK, Eck MJ, Gray NS, Janne PA. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M. Nature. 2009 Dec 24;462(7276):1070-4. PMID:20033049 doi:10.1038/nature08622

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