2fjm

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Image:2fjm.png

Template:STRUCTURE 2fjm

The structure of phosphotyrosine phosphatase 1B in complex with compound 2

Template:ABSTRACT PUBMED 16407290

About this Structure

2FJM is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Asante-Appiah E, Patel S, Desponts C, Taylor JM, Lau C, Dufresne C, Therien M, Friesen R, Becker JW, Leblanc Y, Kennedy BP, Scapin G. Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. J Biol Chem. 2006 Mar 24;281(12):8010-5. Epub 2006 Jan 6. PMID:16407290 doi:10.1074/jbc.M511827200

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