1ijn

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Template:STRUCTURE 1ijn

Contents

Crystal structure of the transthyretin mutant TTR C10A/Y114C

Template:ABSTRACT PUBMED 16185074

Disease

Known disease associated with this structure: Amyloid polyneuropathy, several types OMIM:[176300], Amyloidosis, senile systemic OMIM:[176300], Carpal tunnel syndrome, familial OMIM:[176300], Dystransthyretinemic hyperthyroxinemia OMIM:[176300]

About this Structure

1IJN is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Karlsson A, Olofsson A, Eneqvist T, Sauer-Eriksson AE. Cys114-linked dimers of transthyretin are compatible with amyloid formation. Biochemistry. 2005 Oct 4;44(39):13063-70. PMID:16185074 doi:10.1021/bi050795s

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