3b25

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Template:STRUCTURE 3b25

Hsp90 alpha N-terminal domain in complex with an inhibitor CH4675194

Template:ABSTRACT PUBMED 21875802

About this Structure

3b25 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Miura T, Fukami TA, Hasegawa K, Ono N, Suda A, Shindo H, Yoon DO, Kim SJ, Na YJ, Aoki Y, Shimma N, Tsukuda T, Shiratori Y. Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5778-83. Epub 2011 Aug 6. PMID:21875802 doi:10.1016/j.bmcl.2011.08.001

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