3lc3

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Image:3lc3.png

Template:STRUCTURE 3lc3

Contents

Benzothiophene Inhibitors of Factor IXa

Template:ABSTRACT PUBMED 20121198

Disease

Known disease associated with this structure: Hemophilia B OMIM:[300746]

About this Structure

3LC3 is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wang S, Beck R, Blench T, Burd A, Buxton S, Malic M, Ayele T, Shaikh S, Chahwala S, Chander C, Holland R, Merette S, Zhao L, Blackney M, Watts A. Studies of Benzothiophene Template as Potent Factor IXa (FIXa) Inhibitors in Thrombosis. J Med Chem. 2010 Feb 25;53(4):1465-72. PMID:20121198 doi:10.1021/jm901475e

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