1hbz
From Proteopedia
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CATALASE FROM MICROCOCCUS LYSODEIKTICU
Overview
The three-dimensional crystal structure of catalase from Micrococcus, lysodeikticus has been solved by multiple isomorphous replacement and, refined at 1.5 A resolution. The subunit of the tetrameric molecule of 222, symmetry consists of a single polypeptide chain of about 500 amino acid, residues and one haem group. The crystals belong to space group P4(2)2(1)2, with unit cell parameters a = b = 106.7 A, c = 106.3 A, and there is one, subunit of the tetramer per asymmetric unit. The amino acid sequence has, been tentatively determined by computer graphics model building and, comparison with the known three-dimensional structure of beef liver, catalase and sequences of several other catalases. The atomic model has, been refined by Hendrickson and Konnert's least-squares minimisation, against 94,315 reflections between 8 A and 1.5 A. The final model consists, of 3,977 non-hydrogen atoms of the protein and haem group, 426 water, molecules and one sulphate ion. The secondary and tertiary structures of, the bacterial catalase have been analyzed and a comparison with the, structure of beef liver catalase has been made.
About this Structure
1HBZ is a Single protein structure of sequence from Micrococcus luteus with and as ligands. Active as Catalase, with EC number 1.11.1.6 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Three-dimensional structure of catalase from Micrococcus lysodeikticus at 1.5 A resolution., Murshudov GN, Melik-Adamyan WR, Grebenko AI, Barynin VV, Vagin AA, Vainshtein BK, Dauter Z, Wilson KS, FEBS Lett. 1992 Nov 9;312(2-3):127-31. PMID:1426241
Page seeded by OCA on Sun Feb 3 09:48:28 2008
