2off

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Image:2off.png

Template:STRUCTURE 2off

The crystal structure of Glycogen Phosphorylase b in complex with a potent allosteric inhibitor

Template:ABSTRACT PUBMED 17600143

About this Structure

2OFF is a 1 chain structure of sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

  • Tiraidis C, Alexacou KM, Zographos SE, Leonidas DD, Gimisis T, Oikonomakos NG. FR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylase. Protein Sci. 2007 Aug;16(8):1773-82. Epub 2007 Jun 28. PMID:17600143 doi:10.1110/ps.072925607

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