2af2

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Template:STRUCTURE 2af2

Contents

Solution structure of disulfide reduced and copper depleted Human Superoxide Dismutase

Template:ABSTRACT PUBMED 16291742

Disease

Known disease associated with this structure: Amyotrophic lateral sclerosis, due to SOD1 deficiency OMIM:[147450]

About this Structure

2AF2 is a 2 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Banci L, Bertini I, Cantini F, D'Amelio N, Gaggelli E. Human SOD1 before harboring the catalytic metal: solution structure of copper-depleted, disulfide-reduced form. J Biol Chem. 2006 Jan 27;281(4):2333-7. Epub 2005 Nov 14. PMID:16291742 doi:http://dx.doi.org/10.1074/jbc.M506497200

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