2foq

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Image:2foq.png

Template:STRUCTURE 2foq

Contents

Human Carbonic Anhydrase II complexed with two-prong inhibitors

Template:ABSTRACT PUBMED 16506782

Disease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this Structure

2FOQ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jude KM, Banerjee AL, Haldar MK, Manokaran S, Roy B, Mallik S, Srivastava DK, Christianson DW. Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with "two-prong" inhibitors reveal the molecular basis of high affinity. J Am Chem Soc. 2006 Mar 8;128(9):3011-8. PMID:16506782 doi:http://dx.doi.org/10.1021/ja057257n

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