3zt3

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Template:STRUCTURE 3zt3

Small molecule inhibitors of the LEDGF site of HIV type 1 integrase identified by fragment screening and structure based drug design

Template:ABSTRACT PUBMED 21602613

About this Structure

3zt3 is a 2 chain structure with sequence from Human immunodeficiency virus. Full crystallographic information is available from OCA.

Reference

  • Rhodes DI, Peat TS, Vandegraaff N, Jeevarajah D, Le G, Jones ED, Smith JA, Coates JA, Winfield LJ, Thienthong N, Newman J, Lucent D, Ryan JH, Savage GP, Francis CL, Deadman JJ. Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design. Antivir Chem Chemother. 2011 Mar 7;21(4):155-68. PMID:21602613 doi:10.3851/IMP1716

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