3udd

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Template:STRUCTURE 3udd

Tankyrase-1 in complex with small molecule inhibitor

Template:ABSTRACT PUBMED 22260203

About this Structure

3udd is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Shultz MD, Kirby CA, Stams T, Chin DN, Blank J, Charlat O, Cheng H, Cheung AK, Feng Y, Fortin PD, Hood T, Tyagi V, Xu M, Zhang B, Shao W. [1,2,4]Triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: Antagonists of the Wnt pathway that inhibit tankyrase 1&2 via novel adenosine pocket binding. J Med Chem. 2012 Jan 19. PMID:22260203 doi:10.1021/jm2011222

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